
How to Clean and Sanitize Nasal Cannulas: A Step-by-Step Guide for Safe Oxygen Therapy
Maintaining clean and hygienic oxygen delivery equipment is vital for everyone relying on supplemental oxygen—whether adults, children, or newborns. Nasal cannulas, including the 4-foot, 7-foot (soft and pediatric), and 25-foot varieties, are the most common interfaces, and keeping them sanitized ensures your safety, comfort, and overall health.
If you’re using any of the following:
- 4-Foot Soft Cannula
- 25-Foot Cannula
- 7-Foot Soft Cannula
- 7-Foot Neonatal Cannula
- 7-Foot Pediatric Cannula
…you’re in the right place. You can also explore our full collection of oxygen accessories on our Buy Oxygen Accessories page.
Why Sanitize Your Nasal Cannula?
- Prevent Infections – Bacteria, mold, and other pathogens thrive in moist environments like oxygen tubing.
- Ensure Effective Oxygen Delivery – Buildup of debris can impair airflow.
- Enhance Longevity and Comfort – Clean surfaces are softer, reducing irritation on the nose and face.
Supplies You’ll Need
- Mild dish soap (fragrance-free, dye-free)
- Warm (not hot) water
- A clean basin or sink
- Clean, absorbent towels
- Hydrogen peroxide (optional, for deeper sanitization)
- Optional: Vinegar solution (1 part vinegar to 3 parts water)
Step 1: Remove the Cannula
Gently disconnect the cannula (4-Foot Soft Cannula, 7-Foot Soft, 7-Foot Neonatal, 7-Foot Pediatric, or 25-Foot Cannula) from the oxygen source. Avoid stretching or bending the tubing to maintain its integrity.
Step 2: Clean with Soap and Water
- Fill a basin with warm water and add a drop of mild dish soap.
- Swish the cannula gently in the soapy water to remove oils, particles, and dust.
- Pay extra attention to the prongs—use your fingers or a soft cloth to wipe lightly.
Step 3: Rinse Thoroughly
Rinse the cannula under running warm water until all soap is gone. Let water flush gently through the tubing to clear residue.
Step 4: Optional Disinfection (Weekly Deep Clean)
For a deeper sanitize—especially for infants or those with compromised immunity—try:
Hydrogen Peroxide Method
- Mix 1 part 3% hydrogen peroxide with 2 parts water.
- Soak the cannula for 10 minutes.
- Rinse thoroughly with warm water.
Vinegar Method
- Mix 1 part white vinegar with 3 parts water.
- Soak the cannula for 15 minutes.
- Rinse thoroughly before reuse.
Tip: Avoid bleach or harsh disinfectants—they can damage plastic and irritate skin.
Step 5: Dry Completely
- Shake out excess water.
- Lay flat on a clean towel, untwisted.
- Air-dry fully in a ventilated space away from direct sunlight.
Step 6: Reattach and Store Properly
Once dry, reattach your cannula carefully, avoiding sharp bends. If traveling, coil loosely for storage. To keep spares ready, visit our Oxygen Accessories page.
Cleaning Frequency Guide
| User Type | Cleaning Frequency |
|---|---|
| Adults (healthy) | Soap & water daily Disinfect weekly |
| Children | Soap & water daily Disinfect twice weekly |
| Infants / Neonatal | Soap & water daily Disinfect 2–3× per week |
| During illness or higher exposure | Soap & water after each use Disinfect daily |
Specialized Tips for Different Cannula Types
4-Foot Soft Cannula
Compact and easy for home or travel. Coil gently for storage.
7-Foot Soft Cannula

Gives extra movement flexibility. Take care to dry tubing fully.
25-Foot Cannula
Best for stationary setups. Dry in sections to prevent trapped water.
7-Foot Neonatal & Pediatric Cannulas

Extremely delicate—inspect closely for stiffness or wear. Always handle with care.
Why This Routine Matters
- Safety First – Prevents infections and irritation.
- Performance – Keeps oxygen delivery efficient.
- Longevity – Avoids brittleness and discoloration.
- Peace of Mind – Consistent cleaning means healthier breathing.
Summary: Quick Reference
- Remove and inspect your cannula.
- Wash with soap and water; rinse well.
- Disinfect weekly with peroxide or vinegar solution.
- Rinse again and let air-dry fully.
- Reattach carefully and avoid kinks.
- Follow a schedule based on your needs.
Final Thoughts
Caring for your nasal cannula—whether it’s a compact 4-foot, a flexible 7-foot, a delicate neonatal, or a longer 25-foot—goes beyond maintenance. A clean cannula means safer, more comfortable oxygen therapy. By sticking to this routine, you’ll make every breath count.
For more supplies or replacement options, visit our oxygen accessories collection today.